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doi: 10.1038/S41433-024-03101-5 83 JungBJLeeMYJeonS

O.et al (2025)

These effects are particularly beneficial for individuals with GH deficiency or those seeking to improve their athletic performance and overall health

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The reduction in calories is linked to a lower sex drive because it can significantly reduce the production of sex hormones like testosterone and estrogen, which are crucial for libido, as the body prioritizes essential functions over reproductive ones when in a calorie deficit

Fortunately, clinical research shows that supplemental DIM assists liver enzymes during phase I and phase II to detoxify estrogen, direct it towards the 2-hydroxy pathway, and help shuttle estrogen metabolites and xenoestrogens (like estrogen mimics found in plastics and other environmental chemicals) more efficiently.5-7 The downstream effects of this cant be overestimated